abstract：:The treatment outcomes of 956 women undergoing second trimester termination of pregnancy with mifepristone and gemeprost were studied. The median gestational age was 16 weeks (range: 12-24 weeks). All women were treated with 200 mg mifepristone orally, followed 36 h later with 1 mg vaginal gemeprost administered every...

journal_title：Contraception

authors： Tang OS,Thong KJ,Baird DT

更新日期：2001-07-01 00:00:00

abstract：:Changes in body weight and the incidence of estrogen-related side effects with low-dose oral contraceptives (OCs) containing 20 microg ethinyl estradiol (EE) have not been demonstrated in placebo-controlled trials. Two placebo-controlled, randomized trials demonstrated the efficacy of a low-dose OC for the treatment o...

journal_title：Contraception

authors： Coney P,Washenik K,Langley RG,DiGiovanna JJ,Harrison DD

更新日期：2001-06-01 00:00:00

abstract：:DL111-IT, a non-hormonal contragestional agent, revealed synergistic effects in combination with mifepristone (RU486) in some species. The present study was undertaken to clarify the role of DL111-IT when used alone or plus RU486 on uterine polyamines biosynthesis, histologic alteration of decidual cells, and antifert...

journal_title：Contraception

authors： Shentu J,Zhou H,He Q,Wang L,Fang R

更新日期：2001-05-01 00:00:00

abstract：:As research has shown that knowledge concerning the health risks and benefits of oral contraceptive (OC) use is a contributor to OC compliance, the following study examined an educated sample of young women to determine the level of knowledge concerning the risks and benefits of OC use. A 28-item questionnaire was dev...

journal_title：Contraception

authors： Bryden PJ,Fletcher P

更新日期：2001-04-01 00:00:00

abstract：:Barrier contraceptive trials and disease intervention studies often utilize coital diaries to measure sexual exposures: dates and frequency of intercourse, product use, additional or alternative contraceptive use, and menstrual bleeding. The validity of these self-reported data is a matter of debate, but if used, bett...

journal_title：Contraception

authors： Hays MA,Irsula B,McMullen SL,Feldblum PJ

更新日期：2001-03-01 00:00:00

abstract：:The pharmacokinetics and androgenic activity of Estrostep, a new oral contraceptive providing low-dose estrogen in a graduated sequence with a constant dose of progestin, were characterized in an open-label, nonrandomized study in 17 normally cycling women treated for three cycles with Estrostep. Women received 1 mg o...

journal_title：Contraception

authors： Boyd RA,Zegarac EA,Posvar EL,Flack MR

更新日期：2001-02-01 00:00:00

abstract：:The interceptive effect of the powder of Solanum lycocarpum (St. Hil) (Solanaceae) fruit, used as a hypoglycemic agent by diabetic patients in Minas Gerais state (Brazil), was evaluated to observe possible effects upon zygote and pre-embryo transport in rats, since it contains solamargine and solasonine from which a 3...

journal_title：Contraception

authors： Peters VM,Pinheiro NL,Reis JE,Guerra MO

更新日期：2001-01-01 00:00:00

abstract：:The rheological properties of 4 commercially available contraceptive drug delivery gels and their dilutions with a vaginal fluid simulant were measured. These properties govern the critical functions of spreading and retention of these gels over the vaginal surfaces. Measurements made on Conceptrol, KY Plus, Gynol II,...

journal_title：Contraception

authors： Owen DH,Peters JJ,Katz DF

更新日期：2000-12-01 00:00:00

abstract：:To compare the effectiveness and safety of the Filshie Clip System and Hulka Clip System when applied via minilaparotomy and laparoscopy, we conducted 2 multicenter randomized controlled trials of 2126 women (878 in the minilaparotomy study and 1248 in the laparoscopy study) who received either the Filshie or Hulka Cl...

journal_title：Contraception

authors： Dominik R,Gates D,Sokal D,Cordero M,Lasso de la Vega J,Remes Ruiz A,Thambu J,Lim D,Louissaint S,Galvez RS,Uribe L,Zighelboim I

更新日期：2000-10-01 00:00:00

abstract：:The objective of this study was to compare cycle control, efficacy and tolerance of an oral contraceptive containing 20 microg ethinylestradiol and 150 microg desogestrel with a preparation containing 30 microg ethinylestradiol combined with 75 microg gestodene. This study involved 342 women and 4104 cycles use in Arg...

journal_title：Contraception

authors： Bassol S,Alvarado A,Celis C,Cravioto MC,Peralta O,Montaño R,Novelli J,Albornoz H,Kesseru E,Soares A,Petracco A,Isaia B,Mendes J,Bahamondes L,de Melo NR,Reyes-Marquez R,Albrecht G

更新日期：2000-09-01 00:00:00

abstract：:Testosterone (T) treatment suppresses serum gonadotropins and reduces sperm output sufficiently for contraceptive efficacy in approximately 70% of Caucasian men. In the remaining 30% of men, an increase in 5alpha-reductase activity may maintain testicular androgen activity, thus accounting for the failure of sperm sup...

journal_title：Contraception

authors： McLachlan RI,McDonald J,Rushford D,Robertson DM,Garrett C,Baker HW

更新日期：2000-08-01 00:00:00

abstract：:A number of case-control studies published in recent years have shown an apparent increase in the risk of venous thromboembolism (VTE) associated with the use of third-generation oral contraceptives (OCs) compared with second-generation OCs. However, it is thought that these studies were subject to a number of biases ...

journal_title：Contraception

authors： Heinemann LA

更新日期：2000-08-01 00:00:00

abstract：:After more than a century of reliance on latex condoms, male condoms fabricated from new materials are finally becoming commercially available to consumers. This study was an open label acceptability study that compared three lubricated condom products during vaginal intercourse: a natural rubber latex condom, a polyu...

journal_title：Contraception

authors： Frezieres RG,Walsh TL

更新日期：2000-06-01 00:00:00

abstract：:We evaluated the efficacy and side effects of immediate postcoital administration of levonorgestrel 0.75 mg used repeatedly for contraception. A total of 295 healthy women with infrequent coitus were enrolled at 6 study sites. Each woman took levonorgestrel 0.75 mg by mouth immediately after intercourse during 6 month...

journal_title：Contraception

authors：

更新日期：2000-05-01 00:00:00

abstract：:The aim of this study was to evaluate the effectiveness of lactational amenorrhoea and to determine the relationship between extended breastfeeding and the return of fertility. Breastfeeding pattern, basal body temperature, cervical mucus, salivary ferning, vaginal blood discharge, frequency of sexual intercourse, and...

journal_title：Contraception

authors： Tommaselli GA,Guida M,Palomba S,Barbato M,Nappi C

更新日期：2000-04-01 00:00:00

abstract：:As part of a 60-week, open-label, nonrandomized, parallel, controlled study comparing a monthly contraceptive injection containing medroxyprogesterone acetate (MPA) 25 mg and estradiol cypionate (E(2)C) 5 mg (Lunelle Monthly Contraceptive Injection) and a norethindrone 0.5, 0.75, 1.0 mg/0.035 mg ethinyl estradiol (NET...

journal_title：Contraception

authors： Cromie MA,Maile MH,Wajszczuk CP

更新日期：2000-01-01 00:00:00

abstract：:A study was undertaken to determine whether the combination of oral tamoxifen and moistened misoprostol administered vaginally was superior to that of placebo and moistened misoprostol administered vaginally for elective termination of early pregnancies.A clinical trial was conducted with a study group of 150 healthy ...

journal_title：Contraception

authors： Jain JK,Meckstroth KR,Park M,Mishell DR Jr

更新日期：1999-12-01 00:00:00

abstract：:This open, randomized study was intended to assess the effects of the new single-rod contraceptive implant (Implanon) containing etonogestrel on lipid metabolism in Indonesian women, in comparison with the six-rod implant Norplant, containing levonorgestrel. The effects of both products were compared with a control gr...

journal_title：Contraception

authors： Suherman SK,Affandi B,Korver T

更新日期：1999-11-01 00:00:00

abstract：:Emergency contraception promises to reduce Mexico's high unwanted pregnancy and unsafe abortion rates. Because oral contraceptives are sold over-the-counter, several emergency contraceptive regimens are already potentially available to those women who know about the method. Soon, specially packaged emergency contracep...

journal_title：Contraception

authors： Langer A,Harper C,Garcia-Barrios C,Schiavon R,Heimburger A,Elul B,Renoso Delgado S,Ellertson C

更新日期：1999-10-01 00:00:00

abstract：:A prospective, randomized clinical trial observed the effects of Norplant long-term contraceptive implants and domestic implants similar to Norplant on bone mineral density and bone metabolism in female acceptors for 1 year. Bone mineral density (BMD) and bone mineral content (BMC) of lumbar 2-4 and proximal femur of ...

journal_title：Contraception

authors： Di X,Li Y,Zhang C,Jiang J,Gu S

更新日期：1999-09-01 00:00:00

abstract：:The presence of medical conditions that might affect the use of depot-medroxyprogesterone acetate (DMPA) as a contraceptive method was assessed in a rural district in Nepal. A general health survey was conducted in nonpregnant and noncontracepting women aged 15-44 years to determine the presence of any health problems...

journal_title：Contraception

authors： Rai C,Thapa S,Day J,Bhattarai L,McMullen S,Jha R,Shrestha S,Bastola S,Rivera R

更新日期：1999-07-01 00:00:00

abstract：:Associations between Depo-Provera (injectable, progesterone-only contraceptive) use and visible disruption of cervical epithelium and cervical ectopy were investigated using data collected as part of a cervical cancer screening study in periurban Cape Town, South Africa. Women were interviewed about their contraceptiv...

journal_title：Contraception

authors： Kuhn L,Denny L,Pollack AE,Wright TC

更新日期：1999-06-01 00:00:00

abstract：:User satisfaction and the physical and psychological effects of five commonly used contraceptive methods were investigated in a population survey among 1466 West German women. The focus was on effects attributed by current and past users to these methods, rather than objectively assessed effects, to shed further light...

journal_title：Contraception

authors： Oddens BJ

更新日期：1999-05-01 00:00:00

abstract：:A cross-sectional descriptive study on knowledge, attitudes, and practice about emergency contraception (EC) was conducted among nurses and nursing students using a self-administered questionnaire. One-hundred-sixty-seven qualified nurses and 63 nursing students completed the questionnaire. Over 95% listed at least on...

journal_title：Contraception

authors： Gichangi PB,Karanja JG,Kigondu CS,Fonck K,Temmerman M

更新日期：1999-04-01 00:00:00

abstract：:Intrauterine devices (IUD) provide effective contraception. The current study evaluates the concentration of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) in the intrauterine fluid of postmenopausal women using an intrauterine delivery system releasing progesterone (IDS-P). Intrauterine fluid was ob...

journal_title：Contraception

authors： Archer DF,DeSoto KR,Baker JM

更新日期：1999-03-01 00:00:00

abstract：:There is considerable variation in opinion about the importance of drug interactions between the combined oral contraceptive pill (COCP) and broad-spectrum antibiotics. Clinical practice varies widely, especially between doctors in Europe and those in the US. Rifampicin and griseofulvin induce hepatic enzymes and do a...

journal_title：Contraception

authors： Weaver K,Glasier A

更新日期：1999-02-01 00:00:00

abstract：:This was a dual-cohort study performed to determine if, by using methotrexate alone, abortions could be induced with fewer side effects, without sacrificing effectiveness and patient satisfaction. The subjects were 358 consecutive patients who requested elective medical termination of pregnancy at < 7 weeks gestation....

journal_title：Contraception

authors： Wiebe ER

更新日期：1999-01-01 00:00:00

abstract：:Introduction of the birth control pill in the United States in 1960 marked the end of a relatively short period of time (< 10 years) to intentionally produce an oral contraceptive, and the beginning of a relatively long period of controversy surrounding the use of the pill. Availability of the pill had an impact on va...

journal_title：Contraception

authors： Tyrer L

更新日期：1999-01-01 00:00:00

abstract：:Although weight gain is among the most common complaints of women using oral contraceptives (OC) and a frequent reason for discontinuation, studies demonstrate little basis for this perception. We explored this issue by analyzing the daily weights of 128 women during four cycles of triphasic OC use. The mean weight at...

journal_title：Contraception

authors： Rosenberg M

更新日期：1998-12-01 00:00:00

abstract：:The vaginal bleeding patterns observed during the use of the single-rod progestin-only implant, Implanon, compared with those seen during the use of the six-capsule implant, Norplant, have been analyzed. The acceptability of these bleeding patterns was also assessed. An integrated analysis of 13 different trials was d...

journal_title：Contraception

authors： Affandi B

更新日期：1998-12-01 00:00:00

abstract：:Researchers, health care providers, women's health advocates, donors, and representatives of ministries of health convened in Bellagio, Italy, in July 1998, to assess the potential of medical methods of early pregnancy termination to improve the reproductive health of women in developing countries. Consensus was reac...

journal_title：Contraception

authors：

更新日期：1998-11-01 00:00:00

abstract：:A prospective randomized trial was conducted in 140 women to compare the efficacy of vaginal gemeprost with vaginal misoprostol for termination of second trimester pregnancy. Women requesting termination of second trimester pregnancy were randomized into two groups. Group A women were given 1 mg vaginal gemeprost ever...

journal_title：Contraception

authors： Wong KS,Ngai CS,Wong AY,Tang LC,Ho PC

更新日期：1998-10-01 00:00:00

abstract：:The aim of this prospective study was the follow-up for 2 years in symptoms, serum prolactin (PRL) levels, and radiological aspects of a group of young patients using oral contraceptives (OC) with hyperprolactinemia. A total of 16 hyperprolactinemic women (eight with idiopathic hyperprolactinemia and eight with pituit...

journal_title：Contraception

authors： Testa G,Vegetti W,Motta T,Alagna F,Bianchedi D,Carlucci C,Bianchi M,Parazzini F,Crosignani PG

更新日期：1998-08-01 00:00:00

abstract：:A large introductory study of Cyclofem, a once-a-month injectable contraceptive, was conducted in three Mexican provinces. A total of 3457 healthy women participated: 640 women from rural areas (community-based component) and 2817 women from urban and suburban areas (health center-based component). A total of 20,316 w...

journal_title：Contraception

authors： Garza-Flores J,Moraks del Olmo A,Fuziwara JL,Figueroa JG,Alonso A,Monroy J,Perez M,Urbina-Fuentes M,Guevara SJ,Cedeno E,Barrios R,Ferman JJ,Medina LM,Velazquez E,Perez-Palacios G

更新日期：1998-07-01 00:00:00

abstract：:A total of 99 premenopausal and 27 postmenopausal women were evaluated to determine the quantity of glandular proliferation resulting from progestin inhibition of estrogen-primed subjects and of subjects without hormonal stimulation. Endometrial glandular proliferation rates were determined by using mitosis counts, pr...

journal_title：Contraception

authors： Moyer DL,Felix JC

更新日期：1998-06-01 00:00:00

abstract：:A group of 120 women with gestations from 64 to 84 days received 800 micrograms of vaginal misoprostol every 24 h for a maximum of three doses without performing postexpulsion systematic preventive curettage. Outcome measures included successful abortion (complete abortion without requiring a surgical procedure), side...

journal_title：Contraception

authors： Carbonell Esteve JL,Varela L,Velazco A,Cabezas E,Tanda R,Sánchez C

更新日期：1998-05-01 00:00:00

abstract：:The long-term effects of tolnidamine on male reproduction and general body metabolism were studied in rabbits (Oryctolagus cuniculus). The study was divided into three groups of 10 animals each. The first group (A) received vehicle alone to serve as controls. The second and third groups (B and C) of animals were admin...

journal_title：Contraception

authors： Ansari AS,Kumar Y,Srivastava S,Lohiya NK

更新日期：1998-04-01 00:00:00

abstract：:A variety of epidemiological approaches have been used to assess the safety of steroid contraceptives. Each study design has its own strengths and weaknesses, especially with respect to susceptibility to bias and confounding. Randomized controlled trials provide the strongest evidence of a cause and effect relationshi...

journal_title：Contraception

authors： Hannaford P

更新日期：1998-03-01 00:00:00

abstract：:Changes in the physical characteristics of semen and ultrastructure of the spermatozoa of langur monkeys after vas occlusion with styrene maleic anhydride (SMA), a polymer with pH-lowering action, are reported. Vas occlusion resulted in severe reversible hypospermia. Severe oligospermia was observed in the majority of...

journal_title：Contraception

authors： Lohiya NK,Manivannan B,Mishra PK

更新日期：1998-02-01 00:00:00

abstract：:Levels of inhibin A and B as well as other hormones in serum samples obtained during the pill-free interval in women taking combined oral contraceptives (OC) were measured to asses the extent of ovarian activity during that period. Type of pill and day of pill-free interval were recorded during routine gynecologic che...

journal_title：Contraception

authors： Renier MA,Vereecken A,Van Herck E,Straetmans D,Ramaekers P,Vanderheyden J,Degezelle H,Buytaert P

更新日期：1998-01-01 00:00:00